Principe Felipe Research Center (CIPF)

Principe Felipe Research Center (CIPF) is a cutting-edge biomedical research center located in Valencia. Investigators at the CIPF use a range of model systems to pursue key biological questions related to human health problems including ageing, rare diseases, cancer, neurodegeneration and metabolic diseases. Our mission is to enhance basic knowledge about human diseases with the goal of applying our results to the development of new tools for diagnosis, and drugs for treatments. Our institute also has a new program in gender and biomedical research.

CIPF is a multidisciplinary institute organized in 4 interconnected programs:

Molecular Basis of Human Disease: this program is focused on identification of the molecular causes and mechanisms of several human diseases with emphasis in ageing, rare diseases, metabolic diseases and cancer. It aims to generate knowledge that will improve the diagnosis and the development of specific therapeutic strategies. It promotes a model of translational research and biomedical innovation to drive the development of new tools, biomarkers and therapeutic targets.

Neuroinflammation and Neurological Impairment: This program performs basic and translational research on the mechanisms, diagnosis and treatment of neurological impairment in different pathological situations, including Alzheimer’s Disease, Parkinson, minimal and clinical hepatic encephalopathy in liver cirrhosis, acute liver failure, hyperammonemias, chronic alcohol consumption, alcohol abuse in adolescence and adulthood and perinatal exposure to ethanol (fetal alcohol syndrome) or to food or environmental contaminants.

New Technologies in Biomedical Research: Investigators in this program develop methodologies for high-throughput data analysis and provides software tools for omics studies to understand the functional aspects across different organisms and its relationship with diseases and traits.

Advanced Therapies: The objective of this research area is the development of new diagnostic and therapeutic approaches for health problems through the application of nanotechnology, cell therapy, and medicinal chemistry. This program addressed tools for neoplastic processes, spinal cord injury, musculoskeletal injury, neurodegenerative diseases and new therapies for autoimmune and chronic and inflammatory diseases.

Recently, CIPF has created a transversal program to integrate Gender Research in our institute and to promote the elimination of gender bias in the research community. Precision medicine must include assessment of relevant sex differences and analysis of gender effects in biomedical research.